Perform a Multiple Sequence Alignment with a Profile HMM solved by 35

Sept. 16, 2015, 3 a.m. by Rosalind Team

Topics: HMM

Sequence Alignment with Profile HMM Problem

Given: A string Text, a multiple alignment Alignment, a threshold θ, and a pseudocount σ.

Return: An optimal hidden path emitting Text in HMM(Alignment,θ,σ).

Sample Dataset

AEFDFDC
--------
0.4 0.01
--------
A   B   C   D   E   F
--------
ACDEFACADF
AFDA---CCF
A--EFD-FDC
ACAEF--A-C
ADDEFAAADF

Sample Output

M1 D2 D3 M4 M5 I5 M6 M7 M8

Extra Dataset

Please login to solve this problem.